Here are several high-quality studies linking dental /oral health to Alzheimer’s disease and cognitive decline: 🧠1. Periodontitis & Brain Imaging Markers of Alzheimer's A study involving 468 participants from the WHICAP cohort found that clinical signs of gum disease correlated with MRI markers typical of Alzheimer’s and cognitive aging. Researchers propose that chronic inflammation from periodontitis may contribute to brain changes over time. 2. Umbrella Review: Oral Health & Dementia This comprehensive review of eight systematic studies confirmed consistent associations between poor oral health —like plaque buildup, gingivitis, and periodontal disease—and worsened cognition in dementia patients. The link is largely attributed to systemic inflammation from oral pathogens. 3. Longitudinal Tooth Loss Study in Taiwan A 2025 clinical study in Taiwan examined older adults across Alzheimer's spectrum stages (subjective decline to AD). Results showed that losin...
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